Spontaneous regression and recurrence in a case of nodular fasciitis.

Sir. Nodular fasciitis is a sporadic tumor that results from a benign proliferation of myofibroblasts in soft tissues. It presents clinically as a rapidly-growing firm nodule, most often localized in the subcutaneous tissue (1). While it may arise in any part ofthe body, there is a predilection for the upper extremities, especially the forearms (1-3). Nodular fasciitis occurs most commonly in younger adults, affecting males and females with equal frequency (2—4). Histologie diagnosis of these rapidly growing lesions can be difficult owing to their dense cellularity and high mitotic activity; features shared with some sarcomas (2,5,6). Standard care consists of complete excision, and local recurrences occur very rarely (1-3). Spontaneous regression of nodular fasciitis has been reported, but there are only a few cases documented in the literature, and most often regression followed biopsy or incomplete excision ofthe lesion (7, 8). We describe here an unusual case of nodular fasciitis that regressed spontaneously and recurred after a 5-year interval.